Publications by authors named "E Schepens"

Objective: while smell training appears to be effective for post viral smell loss, its effectiveness in COVID-19 induced smell loss is currently not well known. Therefore, we aim to investigate the potential effect of smell training on patients with COVID-19 induced smell loss.

Methods: we conducted a case-control study with two comparable cohorts.

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  • The Sniffin' Sticks Test (SST) is a validated method for assessing olfactory function, but its length makes it impractical for clinical use, leading to the development of shorter tests like the SST-12 for screening purposes.
  • The study focuses on evaluating the diagnostic accuracy of the SST-12 in detecting olfactory dysfunction in patients who have experienced smell loss after COVID-19.
  • Results show the SST-12 has high sensitivity (93.4%) and reasonable specificity (68.2%), indicating its potential utility in identifying smell loss, although careful interpretation of results is needed in clinical practice.
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  • * Objective measures (TDI scores) showed significant improvement over one year, moving from a baseline score of 21.25 to 30.75, indicating a return to normal olfactory function.
  • * Alongside improved smell perception, self-reported quality of life and gustatory function also showed notable enhancements, suggesting positive recovery trends for COVID-19 patients with lingering olfactory disorders.
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  • - This study investigates the differences in smell and taste disorders between COVID-19 and non-COVID-19 cases, using extensive data from a Dutch biobank involving over 167,000 participants.
  • - The findings show that smell loss is more common and severe in COVID-19 positive individuals, while non-COVID-19 cases mainly report mild symptoms.
  • - Interestingly, although COVID-19 related smell and taste loss is more severe, it tends to have a shorter duration compared to non-COVID-19 related disorders.
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Objective: to determine if the tumor marker squamous cell carcinoma antigen (SCC-Ag) observed over time may contribute to the early detection of recurrence, metastasis, and second primary tumors in the follow-up of patients with head and neck squamous cell carcinoma (HNSCC).

Study Design: A retrospective analysis of patients with HNSCC and at least one SCC-Ag measurement was conducted. Hazard ratios (HRs) were used to determine the correlation between SCC-Ag and an event.

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