Publications by authors named "E Sayar"
Article Synopsis
- - This study examines how levels of Procalcitonin, Tumor Necrosis Factor-alpha, Interleukin-6, and Haptoglobin affect the survival outcomes of calves with diarrhea, categorizing them by severity and type of infection (viral, bacterial, parasitic).
- - A total of 48 diarrheic calves were divided into groups based on their infection type, with blood samples analyzed to track changes over time; the study found a 18.75% mortality rate, with the highest deaths in the severe viral group.
- - The results indicate that Procalcitonin levels can serve as a prognostic biomarker for diarrheic calves, aiding in assessing their conditions across different causes of diarrhea, emphasizing its
Introduction: Leigh syndrome is a rare mitochondrial disorder characterized by subacute necrotizing encephalomyelopathy, resulting from defects in mitochondrial respiratory enzymes or pyruvate dehydrogenase complex. Symptoms can manifest in infancy, childhood, or adulthood. We present a case of a 7-month-old girl initially misdiagnosed with septic shock but was later found to have Leigh encephalomyelopathy due to deficiency.
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- Targeting cell surface molecules with therapies like radioligands and antibodies has been effective in treating various cancers, but the impact of lineage plasticity on these markers is still poorly understood.
- A specific example of lineage plasticity is the transformation of prostate adenocarcinoma to neuroendocrine prostate cancer, which poses significant treatment challenges and worsens patient survival rates.
- Research using advanced single-cell analyses and large tumor sample studies revealed significant phenotypic variability and shared gene-regulatory networks between NEPC and small cell lung cancer, raising concerns about the effectiveness of current therapies while suggesting potential for better patient selection in clinical trials.
Therapeutic approaches targeting proteins on the surface of cancer cells have emerged as an important strategy for precision oncology. To capitalize on the potential impact of drugs targeting surface proteins, detailed knowledge about the expression patterns of the target proteins in tumor tissues is required. In castration-resistant prostate cancer (CRPC), agents targeting prostate-specific membrane antigen (PSMA) have demonstrated clinical activity.
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