Publications by authors named "E Sani"

Background: Studies have reported an association between metabolic dysfunction-associated steatotic liver disease (MASLD) and an increased risk of developing atrial fibrillation (AF). However, the magnitude of the risk and whether this risk varies with the severity of MASLD remains uncertain.

Methods: In this systematic review and meta-analysis, we searched three large electronic databases using predefined keywords to identify cohort studies (published up to 30 September 2024) in which MASLD was diagnosed by liver biopsy, imaging methods, International Classification of Diseases (ICD) codes, or blood-based scores.

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Article Synopsis
  • The study examined the relationship between plasma hepcidin levels and cardiovascular risks in patients with type 2 diabetes mellitus (T2DM) over an average follow-up of 55.6 months.
  • Out of 213 T2DM patients, those with higher hepcidin levels (3rd tertile) had a significantly doubled risk of experiencing adverse cardiovascular outcomes compared to those with lower levels (1st and 2nd tertiles).
  • The association remained strong even after adjusting for various cardiovascular risk factors and other potential confounders, indicating that higher hepcidin could predict increased mortality and cardiovascular events in T2DM patients.
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Wearable sweat sensors can potentially be used to continuously and non-invasively monitor physicochemical biomarkers that contain information related to disease diagnostics and fitness tracking. However, the development of such autonomous sensors faces a number of challenges including achieving steady sweat extraction for continuous and prolonged monitoring, and addressing the high power demands of multifunctional and complex analysis. Here we report an autonomous wearable biosensor that is powered by a perovskite solar cell and can provide continuous and non-invasive metabolic monitoring.

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Aims: Currently, there is little and inconsistent evidence regarding the possible adverse effects of circulating levels of non-esterified fatty acids (NEFA) on kidney function decline in patients with type 2 diabetes mellitus (T2DM).

Methods: We followed for a median of 4.6 years 85 post-menopausal women with non-insulin-treated T2DM and preserved kidney function at baseline.

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