Publications by authors named "E Sandhaus"

Adults with congenital heart diseases may not be candidates for conventional therapies to control ventricular systolic dysfunction, including mechanical circulatory support, which moves potential heart-transplantation recipients to a listing status of higher priority. This results in longer waitlist times and greater mortality rates. Exception-status listing allows a pathway for this complex and anatomically heterogenous group of patients to be listed for heart transplantation at appropriately high listing status.

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Background: Coronavirus disease 2019 (COVID-19) has significantly impacted the healthcare landscape in the United States in a variety of ways including a nation-wide reduction in operative volume. The impact of COVID-19 on the availability of donor organs and the impact on solid organ transplant remains unclear. We examine the impact of COVID-19 on a single, large-volume heart transplant program.

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Article Synopsis
  • The study explores the use of hepatitis C-positive (HCV+) organs for heart/kidney transplants, particularly benefiting patients with both heart failure and kidney issues, starting in 2017.
  • Researchers analyzed data from 39 heart/kidney transplants between 2012 and 2019, comparing outcomes between patients receiving HCV+ organs and those receiving HCV-negative (HCV-) organs.
  • Results showed that while HCV+ recipients had slightly higher creatinine levels shortly after the transplant, their overall survival rates and organ function after one year were similar to those of HCV- recipients, indicating that HCV+ organs can be safely utilized to reduce waitlist times.
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Introduction: Treatment of adult congenital heart disease patients who require advanced therapies remains challenging due to high perioperative and wait-list mortality and limited donors. Patients palliated with Fontan are at the highest risk of early mortality due to multiorgan involvement and few centers able to safely transplant them. We sought to evaluate the early outcomes of heart transplants in these adult Fontan patients.

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