Publications by authors named "E Sanchez-Morla"

Background/objectives: Study of retinal structure based on optical coherence tomography (OCT) data can facilitate early diagnosis of relapsing-remitting multiple sclerosis (RRMS). Although artificial intelligence can provide highly reliable diagnoses, the results obtained must be explainable.

Subjects/methods: The study included 79 recently diagnosed RRMS patients and 69 age matched healthy control subjects.

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Multiple sclerosis (MS) and Alzheimer's disease (AD) cause retinal thinning that is detectable in vivo using optical coherence tomography (OCT). To date, no papers have compared the two diseases in terms of the structural differences they produce in the retina. The purpose of this study is to analyse and compare the neuroretinal structure in MS patients, AD patients and healthy subjects using OCT.

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Article Synopsis
  • The study focuses on identifying new biomarkers for the early diagnosis of multiple sclerosis (MS) using advanced techniques like spectral-domain optical coherence tomography (OCT) and artificial intelligence.
  • Researchers analyzed retinal thickness and differences between the eyes in patients with relapsing-remitting MS and healthy controls to find specific patterns that could indicate MS.
  • The results showed promising accuracy for diagnosing MS: using a convolutional neural network, the study achieved an accuracy of 87%, suggesting that neuroretinal structure analysis might be an important addition to current diagnostic methods for MS.
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Electroconvulsive therapy (ECT) is an effective and safe treatment for severe mental disorders, when it is implemented under an adequate surveillance. Its most frequently described side effects are anterograde amnesia, mania, post- ictal confusion, nausea, headache, myalgia, oral lacerations and dental injuries.

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Delusions are one of the most classical symptoms described in schizophrenia. However, despite delusions are often emotionally charged, they have been investigated using tasks involving non-affective material, such as the Beads task. In this study we compared 30 patients with schizophrenia experiencing delusions with 32 matched controls in their pattern of responses to two versions of the Beads task within a Bayesian framework.

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