Publications by authors named "E Saito"

Background: There are scarce data on risk factors for epithelial ovarian cancer (EOC) in Asian populations. Our goal was to advance knowledge on reproductive -related risk factors for EOC in a large population of Asian women.

Methods: This study used pooled individual data from baseline questionnaires in 11 prospective cohorts (baseline years, 1958-2015) in the Asia Cohort Consortium.

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Article Synopsis
  • Neurodegenerative diseases like Alzheimer's are on the rise due to an aging population and lack of effective early treatments, making early detection crucial for better outcomes.
  • Current diagnostics primarily focus on observable symptoms and existing neuronal damage, while specific biomarkers for Alzheimer's are too narrow, and general biomarkers like NfL lack precise insights.
  • Circulating cell-free DNA (cfDNA) shows promise as a minimally invasive early detection biomarker, providing both general and disease-specific information, but further research is essential to overcome technical challenges and establish its clinical use.
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Background: Coronary artery angiography (CAG) and percutaneous coronary intervention (PCI) are superior to non-invasive approaches in reducing mortality in patients with ST-segment elevation myocardial infarction (STEMI). However, their efficacy remains uncertain in non-ST-elevation acute coronary syndromes (NSTE-ACS) and limited in low-resource settings. This study aimed to compare in-hospital and 5-year mortality rates between patients with a first event of STEMI and NSTE-ACS who underwent CAG and PCI and those with similar severity who did not undergo CAG and PCI.

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We developed the "Itappachi" universal motion platform for measuring radiation doses under simulated respiratory motion in radiation therapy. The interplay effect, resulting from respiratory motion, degrades dose delivery precision in advanced treatments such as volumetric modulated arc therapy. The Itappachi platform is designed for precise dose measurement in dynamic scenarios through its ability to simulate respiratory motion.

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