Publications by authors named "E SCHOLZ"
Article Synopsis
- The study examines the outcomes of cryoballoon-ablation for atrial fibrillation in women, focusing on those with heart failure with preserved ejection fraction (HFpEF) compared to those without.
- Women with HFpEF displayed worse health indicators, including higher left atrial volume, increased left ventricular mass, reduced walking distances, and higher left atrial pressures.
- Results showed that women with HFpEF had more frequent hospitalizations due to AF and did not experience significant improvements in heart failure symptoms or quality of life after the procedure, suggesting they represent a high-risk group.
Article Synopsis
- Immune cells release cytokines, which are crucial for activating the immune response in target cells, but the exact mechanisms behind this process are still being studied.
- This review discusses cytokine secretion through exocytosis, focusing on how cytokines are trafficked and the roles of sorting receptors and cytoskeletal rearrangements in their release.
- It also explores non-classical cytokine release mechanisms, such as inflammasome or autophagy pathways, emphasizing the importance of understanding these processes for potential therapeutic applications in immune-related diseases.
Whole-body distribution of tenofovir, emtricitabine and dolutegravir in non-human primates.
J Antimicrob Chemother
September 2024
Background: One major barrier to HIV cure is the persistence of virus, possibly linked to an insufficient antiretroviral drug (ARV) distribution into tissues.
Objectives: To draw the whole-body distribution of three antiretroviral drugs-tenofovir disoproxil fumarate, emtricitabine and dolutegravir-in non-human primates (NHPs).
Methods: Eight uninfected NHPs received a single injection of a solution containing the three ARVs.
Professional, social, and cultural issues and phenomena of veterinary practice are now established areas of commentary and interest in research, education, professional publications and even in the mainstream media. Despite the availability of theoretically informed literature in diverse relevant domains and disciplines including professional practice, workplace learning, and medical sociology and anthropology, commentary and research on veterinary practice issues and phenomena remains dominated by clinician-educators and clinician-policymakers. Reflecting the clinical disciplinary traditions, there is a resulting over-representation of individualistic, positivist perspectives and under-theorized research studies.
View Article and Find Full Text PDFNumerous culture-based diagnostics are available on the Australian and international markets for on-farm detection of bacterial pathogens in milk. Use of such diagnostics may provide an opportunity to improve the prudent use of antimicrobials in udder health management. Farms are low-resource settings in terms of diagnostic microbiology capacity.
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