[Clinical aspects of metabolic nephropathies, interstitial nephritis and urolithiasis in calciphylaxis].

The problem of abacterial nephropathies associated with impaired calcium metabolism is discussed from the standpoint of membranous pathology. The data are presented on the similarity of the calciphylaxis pathogenesis described for the first time by H. Selye to calcium nephrolithiasis.

[Biologically active metabolites of membrane glycerophospholipids in normal conditions and in pathologic states].

The data on biological role of numerous phospholipid metabolites, main part of which is localized in cell membranes, are reviewed. Many of these metabolites are related to slowly reacting substances of anaphylaxis and participate in allergic and inflammatory reactions. Conditions of biosynthesis of phospholipid active metabolites are characterized in the reactions of lipid peroxidation, N-acetylation, formation of Shiff bases, enaminales via transacetylation, by the action of phospholipases, lipooxygenase, cyclooxygenase, by formation of plasmalogens, phosphomonolipids, phospholipid diols.