Publications by authors named "E S Poole"
Choline is an essential nutrient required for proper functioning of organs and serves as a methyl donor. In liver where choline metabolism primarily occurs, glucose homeostasis is regulated through insulin receptor substrates (IRS) 1 and 2. The objective of this research was to determine the role of prenatal choline as a modulator of metabolic health and DNA methylation in liver of offspring and dams.
View Article and Find Full Text PDFAfter primary infection, human cytomegalovirus (HCMV) establishes lifelong persistence, underpinned by latent carriage of the virus with spontaneous reactivation events. In the immune-competent, primary infection or reactivation from latency rarely causes disease. However, HCMV can cause significant disease in immune-compromised individuals such as immune-suppressed transplant patients.
View Article and Find Full Text PDFAn Interpersonal and Meta-analytic Approach to Parenting Behaviors and Adolescent Sleep.
Clin Child Fam Psychol Rev
December 2024
Two dimensions of parenting behaviors-affiliative/non-affiliative and autonomy/control- are each consistently linked to adolescent sleep health. Parenting behaviors that facilitate good sleep likely involve affiliation (i.e.
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- The study investigates the potential risks of preterm birth (PTB) and low birth weight (LBW) linked to hydraulic fracturing (HF) exposure, specifically looking at how chemicals in HF fluids affect hormone pathways like estrogen and testosterone.
- This is the first national analysis in the US to explore these associations and uses detailed statistical models to examine data from 2001 to 2018 across various counties.
- The research incorporates various factors such as demographics, education, agricultural practices, and health statistics to accurately assess the effects of HF well density and hormone-targeting chemicals on PTB and LBW rates.
Article Synopsis
- Insects carry bacterial communities that significantly influence their metabolism, development, immunity, and overall fitness, yet little is known about the bacteriomes of wireworms, which are significant agricultural pests in Canada.
- This study focused on five major wireworm pest species to analyze their bacterial communities using 16S rRNA sequencing, revealing over 400 genera primarily from four main bacterial phyla.
- The findings indicate that while each species has a small number of predominant genera, the bacterial communities are diverse and their composition is influenced by developmental stages and reproductive strategies, offering insights for future pest management strategies.