[Laryngeal reconstruction after extensive frontolateral resections in locally disseminated laryngeal cancer].

In the department of upper respiratory and gastrointestinal tract tumors of the Russian Cancer Research Center one-stage laryngeal reconstruction after extensive frontal-lateral resection for cancer stage III (T3N0M0) was performed in 11 patients. Two variants of the reconstruction were used: plastic reconstruction of the laryngeal defect with a dermal-muscle graft involving m. sternohyoideus and with down retraction of the epiglottis.

[Statistics and prehospital diagnosis of malignant neoplasms of upper respiratory tract in Russia].

In 1990 in Russia there were 12,264 newly diagnosed cases of upper respiratory tract cancer and 7562 relevant lethal cases. The authors provide data on such cancer incidence rate by site, groups of population, sex, age, type of tumor. Standardized incidence and mortality rates for various regions of Russia are indicative of the trend to the rates increase and relevant economic losses.

[Combined treatment of stage III laryngeal cancer with different schedules of radiotherapy and surgery. Evaluation of preventive methods of the treatment of regional areas (cooperative randomized study)].

In 1980-1987, a cooperative randomized study of 363 patients with stage III laryngeal cancer (T1-3N0-1M0) was carried out. In 249 patients tumor was located in the vestibular space and in 114 in the vocal cord area; 78.5% of the patients had no regional metastases (N0) and 21.

[Comparative evaluation of the effectiveness of radiotherapy, surgery and combined treatment of stage I-II laryngeal cancer (T1-2NoMo) based on the data of a cooperative randomized study].

During 1979-1987 269 patients with laryngeal cancer stage I-II were included into a cooperative randomized study: 111 patients had T1 and 158 patients, T2 tumor; 13% of patients showed cancer of the vestibular cord and 87% of them of the true vocal cord. 76 patients underwent surgery, 129 patients--radiotherapy, and 64 patients received combined treatment, i.e.

[Radiation therapy of stage III laryngeal cancer].

As a result of a marked effect of the 1st stage of radiation therapy of 44 patients with stage III (T3N0M0) laryngeal cancer it was followed by therapy after a radical program up to a summary focal dose of 65-70 Gy. Continued tumor growth and recurrences were diagnosed in 19 patients, of them radical operation was performed on 12, 25 patients (57%) have been followed-up for 3 years, without signs of either recurrence or metastases with the preserved larynx. The above results suggest the effectiveness of radiation therapy in locally advanced laryngeal cancer.