Simultaneous separation and electroanalysis in a single polydimethylsiloxane-based platform.

Channel-based microfluidic devices integrating the separation step and detection system are key factors to expand microanalysis application. However, these devices still depend on macroscale external equipment for pre-treatment of the sample, separation, or detection. The integration of all steps in only one stage is critical to improving feasibility.

Newly designed dual-mode electrochemical sensor onto a single polydimethylsiloxane-based chip.

Here we present a planar polydimethylsiloxane (PDMS)-based millifluidic device in which the channel (at a serpentine-shape) and a new design of electrochemical sensor (dual-mode detection) are assembled into a single chip. The platform makes use of a fully integrated reservoir to place the reference electrode, separating it from the flowing stream. The device was properly characterized aiming to evaluate the influences of channel geometries and diameters, and the electrochemical properties were improved compared with the classical reference electrode configuration.

Direct electrochemical detection of glyphosate at carbon paste electrode and its determination in samples of milk, orange juice, and agricultural formulation.

This paper describes a simple, inexpensive, highly sensitive, selective, and efficient electrochemical method to determine glyphosate (GLY) in samples of milk, orange juice, and agricultural formulation. The oxidation reaction on the electrode surface was electrochemically characterised by cyclic voltammetry (CV) and square wave voltammetry (SWV). The investigation of GLY at carbon paste electrode revealed a non-reversible oxidation peak at +0.

Impact of diet on the immunological microenvironment of the pregnant uterus and its relationship to allergic disease in the offspring--a review of the recent literature.

Medical progress has reduced the mortality from infectious diseases in most countries, but allergic diseases have become more prevalent worldwide over the same period, especially in industrialized countries. This has prompted speculation that modern lifestyles have altered the relationship between heredity and environment so as to promote development of an atopic phenotype when exposure to infection decreases. A healthy uterine microenvironment is known to favor Th2 lymphocyte development.

Contractile cells and fibrillin-1 distribution is disturbed in terminal villi of placentae from patients with preeclampsia and systemic lupus erythematosus.

Placentae from patients with preeclampsia (PE) and systemic lupus erythematosus (SLE) present many alterations that may impair materno-fetal exchange. We investigated the distribution of contractile cells and fibrillin-1 in terminal villi of term placentae from patients with PE or SLE and compared to control placentae. Stroma in terminal villi exhibited intense labelling for fibrillin-1.