Meaning making and fostering radical hope: applying positive psychology to eco-anxiety research in youth.

The consequences of human activity on climate change are increasingly apparent. For example, they are causing ecological degradation and affecting human and animal health. Rightly so, it is considered as the most important challenge of this century.

Greater lesion damage is bidirectionally related with accelerated brain aging after stroke.

Regional neuron loss following stroke can result in remote brain changes due to diaschisis and secondary brain atrophy. Whole brain changes post-stroke can be captured by the predicted brain age difference (brain-PAD), a neuroimaging-derived biomarker of global brain health previously associated with poorer chronic stroke outcomes. We hypothesized that greater lesion damage would be longitudinally associated with worsening brain-PAD during subacute stroke, and conversely, that poorer baseline brain-PAD would be associated with enlarged lesion damage.

Global deletion of the immune cell transcription factor, T-bet, alters gut microbiota and insulin sensitivity in mice.

The gut microbiota plays a role in energy homeostasis: its composition differs in lean and obese mice and may impact insulin sensitivity. The immune system has co-evolved with the gut microbiota, but direct regulation of microbial communities by the immune system and its metabolic impact is unclear. Mice lacking the immune cell specific transcription factor T-bet (Tbx21) are insulin sensitive.

Monitoring of greenhouse gas emissions and compost quality during olive mill waste co-composting at industrial scale: The effect of N and C sources.

Olive mill wastes (OMW) management by composting allows to obtain valuable fertilizing products, but also implies significant fluxes of greenhouse gases (GHG). For a proper OMW composting, high C- and N co-substrates are necessary, but little is known concerning their effect on GHG emissions in OMW-industrial scale composting. In this study, different co-composting agents (cattle manure (CM), poultry manure (PM), sheep manure (SM) and pig slurry solid fraction (PSSF) as N sources and olive leaves (OLW) and urban pruning residues (UPR) as bulking agents and C sources) were used for OMW composting at industrial scale.

Clinical Utility of a Digital Dermoscopy Image-Based Artificial Intelligence Device in the Diagnosis and Management of Skin Cancer by Dermatologists.

Background: Patients with skin lesions suspicious for skin cancer or atypical melanocytic nevi of uncertain malignant potential often present to dermatologists, who may have variable dermoscopy triage clinical experience.

Objective: To evaluate the clinical utility of a digital dermoscopy image-based artificial intelligence algorithm (DDI-AI device) on the diagnosis and management of skin cancers by dermatologists.

Methods: Thirty-six United States board-certified dermatologists evaluated 50 clinical images and 50 digital dermoscopy images of the same skin lesions (25 malignant and 25 benign), first without and then with knowledge of the DDI-AI device output.