[The development of a nutrient medium for Bifidobacterium bifidum biomass accumulation in continuous cultivation processes in a bioreactor].

A new nutrient medium for the cultivation of bifidobacteria, containing dry nutrient bases of the Bactofoc series, has been developed. The nutrient medium composition has been adjusted by modern methods with the use of a model Bioscreen apparatus permitting the study of growth kinetics in 200 cultivation processes simultaneously. The new nutrient medium has been used in the development of the continuous flow cultivation of bifidobacteria in a bioreactor under anaerobic conditions.

[Ways of improving the effectiveness of bacteriological diagnosis and treatment of nonspecific lung diseases].

Isolation, identification and drug sensitivity assay of microorganisms from pathological materials of 177 patients with nonspecific diseases of the lungs, mainly pneumonia, were performed on blood and selective "chocolate" agars by using Baktofok-MK, a new dry nutrient basis developed by the authors. Blood and "chocolate" agars based on the Hottinger's hydrolysate were used as the control media. It was shown that with the quantitative procedure for inoculating the pathological material, the experimental media based on Baktofok-MK were much more sensitive to growth properties that the control media.

[Clinico-endoscopic characteristics of gastroduodenal Campylobacter infection in children].

During diagnostic esophagogastroduodenoscopy, 104 children aged 6 months to 14 years were subjected to spot biopsy of the mucous membrane of the antral part of the stomach and duodenal bulb with a purpose of subsequent studies for Campylobacter pyloris (C. P.) including primary microscopy, the screening-urease test and culture isolation followed by its identification according to all the necessary biochemical tests.

[Triterpene glycosides with antifungal activity isolated from the sea cucumber, Cucumaria japonica].

A complex of triterpenic oligoglycosides or cucumariosides was isolated from the skin-muscular sac of Cucumaria japonica. The complex includes at least 7 components. Fractionation of the complex on lyophilized sephadex LH-20 resulted in quantitative isolation of its 2 main components, i.