Publications by authors named "E S Breslau"

Background: Screening colonoscopy harms data are limited for adults ages 76-85 years.

Methods: We conducted a retrospective cohort study of screening colonoscopies vs. fecal immunochemical tests (FIT) and general population matched comparators aged 76-85 within 3 integrated healthcare systems (2010-2019).

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Context can influence cancer-related outcomes. For example, health-care organization characteristics, including ownership, leadership, and culture, can affect care access, communication, and patient outcomes. Health-care organization characteristics and other contextual factors can also influence whether and how clinical discoveries reduce cancer incidence, morbidity, and mortality.

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Background: Little evidence exists to guide continuation of screening beyond the recommended ages of national guidelines for breast, cervical, and colorectal cancers, although increasing age and comorbidity burden is likely to reduce the screening benefit of lower mortality.

Objective: Characterize screening after recommended stopping ages, by age and comorbidities in a large, diverse sample.

Design: Serial cross-sectional.

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Article Synopsis
  • Colorectal cancer screening is recommended for adults aged 45 to 75, but there's limited data on whether older adults, especially those with prior screenings, should continue testing.
  • A study of over 118,000 adults aged 76 to 85 found that those with a recent negative fecal occult blood test had very low rates of colorectal cancer incidence and mortality after 2 and 8 years.
  • The results suggest that for older adults with negative screenings, the risk of dying from colorectal cancer is significantly lower than dying from other causes, which can help guide decisions about continued screening past age 75.
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