Publications by authors named "E S Bora"
Resting state functional connectivity in adolescents with substance use disorder and their unaffected siblings.
Psychiatry Res Neuroimaging
December 2024
Article Synopsis
- The study investigates resting-state functional connectivity (rsFC) in adolescents with substance use disorder (SUD), their unaffected siblings, and typically-developing controls to find network organization changes linked to familial SUD risk.
- Adolescents with SUD exhibited both weaker and stronger rsFC, specifically in the default-mode network (DMN) and its connections with other networks, compared to typically-developing controls.
- Although unaffected siblings showed no overall differences from controls, they did present lower rsFC within the DMN and between the visual network and other networks, along with higher rsFC between the DMN and fronto-parietal network, indicating potential familial predispositions for SUD.
Objective: The present meta-analysis aims to assess whether individuals with anorexia nervosa (AN) demonstrate elevated autistic traits, to explore potential associations between autistic traits and eating disorder symptoms; as well as to estimate the prevalence of a positive screen for autism spectrum disorder (ASD) assessed via Autism Diagnostic Observation Schedule (ADOS), in AN.
Method: A systematic literature search was conducted in PsycINFO, MEDLINE, and Web of Science in August 2023 and later updated in April 2024 to identify relevant studies. Twenty-two studies with 1172 AN patients and 2747 healthy controls (HCs) met the inclusion criteria.
A meta-analysis of data-driven cognitive subgroups in bipolar disorder.
Eur Neuropsychopharmacol
January 2025
The delineation of cognitive subgroups of bipolar disorder (BD) might be helpful for identifying biologically valid subtypes of this disorder. This meta-analysis identified peer-reviewed literature on studies investigating cognitive subgroups of BD with data-driven clustering methods. Relevant studies were searched in PubMed, Scopus, and Web of Science.
View Article and Find Full Text PDFAbnormal connectivity in the brain has been linked to the pathophysiology of severe mental illnesses, including bipolar disorder and schizophrenia. The current study aimed to investigate large-scale functional networks and global network metrics in clinical high-risk for bipolardisorder (CHR-BD, n = 25), clinical high-risk for psychosis (CHR-P, n = 30), and healthy controls (HCs, n = 19). Help-seeking youth at CHR-BD and CHR-P were recruited from the early intervention program at Dokuz Eylul University, Izmir, Turkey.
View Article and Find Full Text PDFBackground And Hypothesis: Abnormalities in the retina are observed in psychotic disorders, especially in schizophrenia.
Study Design: Using spectral-domain optical coherence tomography, we investigated structural retinal changes in relatively metabolic risk-free youth with clinical high-risk (CHR, n = 34) and first-episode psychosis (FEP, n = 30) compared with healthy controls (HCs, n = 28).
Study Results: Total retinal macular thickness/volume of the right eye increased in FEP (effect sizes, Cohen's d = 0.