[DYNAMICS OF INFLAMMATORY MARKERS AFTER SURGERY ON THE DISTAL RECTUM].

Objective - to compare the concentrations of inflammatory markers interleukin-6, CRP, and lactoferrin in the serum of patients with benign diseases of the rectum, depending on the volume of surgical intervention and evaluate their changes in different periods after surgery. Been surveyed 92 patients: 54 patients (control group) were operated on for one of the three diseases - chronic hemorrhoids, fistula rectum and chronic anal fissure, 38 patients (main group) operated simultaneously over two or more diseases (combined pathology), where the main were diagnosed with the above diseases. In both groups of patients was determined concentration of interleukin-6, CRP and lactoferrin in serum before surgery, on 3 and 7 days after surgery.

[A meta-analysis of clinical studies in otorhinolaryngology].

The Objective: Of the work was to describe the basics of a meta-analysis with features for evaluating models with fixed and random effects, to present principles for interpreting the graphical results of a meta-analysis (forest plot or blobogram) of comparative reviews of randomized clinical trials (RCTs).

Material And Methods: To illustrate the possibility of efficient use of the R software environment for meta-analysis, we used the results of RCTs of various tonsillectomy methods already published in the Cochrane Database review.

Results: The article provides explanations for the calculation of effect size, heterogeneity statistic, and other meta-analysis statistics and their interpretation for evaluating RCTs and recommendations for choosing a model depending on the on the general research concept.

The new combination of risk factors determining a high risk of gestational diabetes mellitus.

Aim: The aim of this study was to identify early markers of gestational diabetes mellitus (GDM) and to reveal the most significant of them.

Methods: A total of 548 pregnant women were screened for GDM between weeks 24 and 28 of gestation, as defined by International Association of Diabetes In Pregnancy Study Groups (IADPSG) criteria, in a retrospective case-control study. First trimester maternal fasting glucose, anthropometric parameters and blood pressure were obtained from medical records.