Publications by authors named "E Roldan-Valadez"
Background: Castleman disease (CD) is a rare lymphoproliferative disorder, with intracranial involvement being exceedingly rare. Unicentric Castleman disease (UCD) is typically benign and localized, but its presentation can mimic other intracranial pathologies, complicating diagnosis.
Case Description: We reported a 52-year-old woman who presented with progressive headaches and language disturbances.
Background: Diagnosing periprosthetic joint infection (PJI) remains a significant challenge for healthcare professionals. Commonly utilized inflammatory markers include erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and white blood cells (WBC). Human -defensin 1 (-defensin) is an antimicrobial peptide elevated in infection, yet its diagnostic value for PJI has not been explored.
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- * Dysregulation of tryptophan (Trp) metabolism plays a role in FM, as Trp is crucial for serotonin production and is involved in immune responses via the kynurenine pathway, affecting mood and pain perception.
- * The review suggests a new treatment strategy for FM by inhibiting the synthesis of neurotoxic quinolinic acid (QA) and using selective serotonin reuptake inhibitors to elevate protective kynurenic acid (KYNA) levels, aiming to reduce pain and improve mental health outcomes.
Background: Pulmonary arterial hypertension (PAH) is a major concern in patients with Down syndrome (DS) and congenital heart disease (CHD). Understanding the unique characteristics of PAH in these populations is essential for developing tailored management strategies. This review examines differences in PAH between DS and non-DS (nDS) patients with CHD, focusing on pathophysiology, clinical presentation, hemodynamic profiles, and treatment outcomes.
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