Publications by authors named "E Roach"
Tuberous sclerosis complex: Diagnostic features, surveillance, and therapeutic strategies.
Semin Pediatr Neurol
October 2024
Article Synopsis
- Tuberous sclerosis complex (TSC) is a rare genetic disorder caused by mutations in the TSC1 or TSC2 genes, leading to the abnormal growth of tissues in various organs due to mTOR pathway dysregulation.
- It can cause neurological issues such as brain tumors, drug-resistant epilepsy, developmental delays, and other behavioral challenges.
- The review discusses TSC's clinical manifestations, recommended diagnostic and genetic tests, available treatments, and essential educational and social support resources for affected individuals.
Background: Case analysis is a dynamic and interactive teaching and learning strategy that improves critical thinking and problem-solving skills. However, there is limited evidence about its efficacy as an assessment strategy in nursing education.
Objectives: This study aimed to explore nursing students' perceived efficacy of case analysis as an assessment method for clinical competencies in nursing education.
Background: For breast cancer with advanced regional lymph node involvement, axillary lymph node dissection (ALND) remains the standard of care for staging and treating the axilla despite the presence of undissected lymph nodes. The benefit of ALND in this setting is unknown.
Objectives: We sought to describe national patterns of care of axillary surgery and its association with overall survival (OS) among women with cN2b-N3c breast cancer who receive adjuvant radiotherapy.
Background: Delays in initiating and completing brachytherapy may have adverse oncologic outcomes for patients with cervical, uterine, and prostate cancer. The impact of the COVID-19 pandemic on brachytherapy in the United States has not been well-characterized.
Objectives: We aim to evaluate how a positive COVID-19 test affected timeliness of treatment for patients undergoing brachytherapy for cervical, uterine, and prostate cancer.
A 53-year-old patient with known psoriasis presented with painful erosive plaques in existing psoriasis lesions, ulcerations in the mouth, and leukopenia. She used 10 mg of methotrexate daily without folic acid prophylaxis. During admission she developed pancytopenia, liver failure and acute kidney injury.
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