Publications by authors named "E Reece"

The US biomedical research enterprise is renowned for its historical and ongoing scientific breakthroughs and advancements. Yet its capacity to solve complex health issues, bridge health equity gaps, and strengthen public trust is constrained by the lack of an overarching national vision, fragmented coordination for research funding, and critical workforce recruitment and retention challenges. To improve national health outcomes and retain global competitiveness, the sector must embrace new approaches.

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Background: Vertebral body defects pose a significant challenge in spinal reconstructive surgery. Compression fractures of the vertebral corpus are typically treated with vertebral augmentation procedures. There are significant risks associated with the introduction of foreign material in the spine, including infection and pseudarthrosis.

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Spino-plastic surgery describes a specialized, multidisciplinary approach to addressing various spinal pathologies. The field is the innovative product of a multidisciplinary collaboration between plastic and reconstructive, orthopedic, and neurosurgery. Over the last few decades, this collaboration has borne promising surgical techniques and treatment plans geared toward restoring form, function, and aesthetics in patients with a variety of spinal conditions, including failed fusions, pseudoarthrosis, and the need for oncologic reconstruction.

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Article Synopsis
  • The objective of the study was to explore the signaling pathways originating from the placenta that contribute to spontaneous preterm labor, using advanced techniques like single-cell RNA sequencing.
  • Researchers found that specific pathways, such as ferroptosis and kisspeptin, were activated in distinct cellular clusters of the placenta from preterm births, with a notable increase in the gene PSG4 related to cellular aging.
  • The study concludes that the overexpression of PSG4 could serve as a valuable biomarker for identifying pregnant women at higher risk of preterm delivery, potentially aiding in early interventions.
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