Publications by authors named "E Rask"
Article Synopsis
- - The study examined the prevalence of dumping and post-bariatric hypoglycemia (PBH) symptoms among patients undergoing Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) at Lindesberg Hospital, Sweden, over a 5-year period.
- - Results showed a significant increase in dumping symptoms from 4.9% pre-surgery to 26.3% at 5 years post-surgery for RYGB patients, while PBH symptoms rose from 1.4% to 19.3%.
- - In contrast, SG patients did not experience a significant increase in these symptoms, and persistent type 2 diabetes was found to be a protective factor against PBH symptoms
Whole genome and exome sequencing are reporting on hundreds of thousands of missense mutations. Taking a pan-disease approach, we explored how mutations in intrinsically disordered regions (IDRs) break or generate protein interactions mediated by short linear motifs. We created a peptide-phage display library tiling ~57,000 peptides from the IDRs of the human proteome overlapping 12,301 single nucleotide variants associated with diverse phenotypes including cancer, metabolic diseases and neurological diseases.
View Article and Find Full Text PDFBackground: Symptomatic postbariatric hypoglycemia (PBH) is a known complication that can occur a few years after Roux-en-Y gastric bypass (RYGB). There is currently no established rating scale for PBH-associated symptoms developed for use in Swedish populations. The aim of the study was to translate an already existing questionnaire into Swedish and to test its reliability.
View Article and Find Full Text PDFA Randomized Trial of the Effect of a GnRH Analogue Injection on Ghrelin Levels in Girls.
Horm Res Paediatr
November 2022
Introduction: Ghrelin concentrations decline during puberty by an unclear mechanism. Acylated ghrelin (AG) is unstable in sampling tubes, but no standardized sampling protocol exists. We hypothesized that ghrelin levels decrease as a consequence of increased gonadotropin-releasing hormone (GnRH) signalling and that the addition of a protease inhibitor to sampling tubes preserves the AG levels.
View Article and Find Full Text PDFObjectives: To compare the usefulness of the classical definition of delayed puberty (DP) in boys with puberty nomograms and to describe the management of DP in boys in a hospital-based setting.
Study Design: Observational retrospective multicentre study with a short-term follow-up.
Setting And Participants: Boys diagnosed with DP during 2013-2015 at paediatric departments in four counties in central Sweden.