Objective: Conflicting data exist on the diagnostic sensitivity of core-needle biopsy (CNB) compared to fine-needle aspiration (FNA) in the evaluation of axillary lymph node metastasis from breast cancer. Our purpose was to evaluate the sensitivity of CNB and FNA using subsequent axillary surgery as the gold standard and to compare the patients' subjective pain levels for each biopsy method.
Methods: This IRB-approved prospective study enrolled 140 patients from February 2014 to May 2019 with known or suspected breast cancer.
CMML patients comprise an elderly and frail patient population with comorbidities that often require surgical intervention. Postsurgical leukemoid reaction, a life-threatening complication in CMML patients, may be driven by molecular mechanisms.
View Article and Find Full Text PDFJ Stroke Cerebrovasc Dis
December 2009
Stroke in patients with cancer is second only to metastasis as a cause of focal neurological deficit. Stroke in this setting is usually linked to mucinous tumors or hematologic malignancies. We describe 2 patients with cervical cancer who developed disseminated intravascular coagulation (DIC)-mediated cerebral infarctions.
View Article and Find Full Text PDFJ Stroke Cerebrovasc Dis
December 2009
Unlabelled: Cervene (nalmefene), an opioid antagonist with relative kappa receptor selectivity, has shown neuroprotective effects in multiple experimental central nervous system injury and ischemic models. The agent already has a well-established safety profile in various clinical indications. Results from an earlier pilot study in 44 acute stroke patients suggest that Cervene administered by 24-hour maintenance infusion was safe and tolerable.
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