Publications by authors named "E Rajan"
Background: Multiple management guidelines for intraductal papillary mucinous neoplasms (IPMNs) have been published to improve risk stratification and resource utilization. This study aims to evaluate trends in endoscopic ultrasound (EUS) use and agreement between cross-sectional imaging and EUS for specific pancreas cystic lesion (PCL) features.
Methods: This retrospective cohort study included consecutive adults undergoing EUS for suspected IPMN detected with cross-sectional imaging (CT/MRCP) between 2013 and 2015 (Cohort 1) and 2018-2020 (Cohort 2).
Article Synopsis
- A multicenter study aimed to evaluate the effectiveness of methylated DNA markers (MDMs) found in pancreatic juice (PJ) for detecting pancreatic ductal adenocarcinoma (PDAC) when used alone and in combination with a blood test, CA 19-9.
- The analysis included DNA samples from 88 confirmed PDAC cases and 134 control cases, utilizing logistic regression to summarize accuracy through the area under the receiver-operating characteristic curve (AUROC).
- Results showed that the combination model of PJ-MDMs and CA 19-9 achieved a higher accuracy (AUROC of 0.95) compared to using PJ-MDMs (0.87) or CA 19-9 alone (0
Article Synopsis
- Atrial fibrillation (AF) ablation can lead to serious complications like esophageal injuries, which can create life-threatening fistulas; EUS (Endoscopic Ultrasound) is being explored as a better diagnostic tool than EGD (Esophagogastroduodenoscopy) for detecting these injuries.
- A study of 234 patients showed that EUS effectively identified various conditions post-ablation, including pleural effusions and esophageal wall changes, with a strong association between certain EUS findings and the severity of esophageal injury.
- The findings suggest that EUS is a safe and potentially superior method for evaluating post-ablation injuries in patients, with recommendations for prioritizing EUS over EGD in these
Background And Aims: Although EUS is highly accurate for the evaluation of common bile duct (CBD) dilation, the yield of EUS in patients with incidental CBD dilation is unclear.
Methods: Serial patients undergoing EUS for incidental, dilated CBD (per radiologist, minimum of >6 mm objectively) from 2 academic medical centers without active pancreaticobiliary disease or significantly elevated liver function test results were evaluated. Multivariable logistic regression identified predictors of EUS with significant findings and a novel prediction model was derived from one center, internally validated with bootstrapping, and externally validated at the second center.