Publications by authors named "E Raghava Rao"

Introduction Human papillomavirus (HPV) is the most common causative agent for cervical cancer (CC) in women. Despite extensive initiatives, the acceptance and implementation of vaccinations have remained inadequate, hindering a significant impact on public health outcomes. This study aimed to provide a comprehensive assessment of the knowledge, awareness, and practices (KAP) scores of medical and dental students regarding HPV infection and vaccination.

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The application of extracellular vesicles (EVs) as therapeutics or nanocarriers in cell-free therapies necessitates meticulous evaluations of different features, including their identity, bioactivity, batch-to-batch reproducibility, and stability. Given the inherent heterogeneity in EV preparations, this assessment demands sensitive functional assays to provide key quality control metrics, complementing established methods to ensure that EV preparations meet the required functionality and quality standards. Here, we introduce the detectEV assay, an enzymatic-based approach for assessing EV luminal cargo bioactivity and membrane integrity.

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Objectives: Innovative therapy is common in many areas of medicine. Yet, it is unknown whether medical centers have policies to ensure innovative therapy is conducted appropriately.

Design: We contacted three informants at leading U.

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Article Synopsis
  • B7-H3 is a protein that is overexpressed in renal cell carcinoma (RCC) but not in normal tissues, making it a good target for cancer therapies.
  • Researchers created advanced CAR-T cells that specifically target B7-H3, showing strong effectiveness against RCC tumors in lab tests and mouse models.
  • The CAR-T cells demonstrated significant growth and impressive cytokine release when interacting with RCC cells, suggesting a promising new treatment approach for patients with RCC.
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