Publications by authors named "E Rabe"

Aim of this study was to analyze the effect of medical compression stockings (MCS) class I (according to the German classification "RAL-GZ 387"; 18-21 mmHg) on symptoms in patients with uncomplicated varicose veins (C2s-C4a). We conducted a randomized (1:1), controlled, clinical trial enrolling patients with uncomplicated varicose veins (CEAP: C2s-C4a). The study consisted of a one-week baseline period and a four-week follow-up period with MCS treatment (compression class I, 18-21 mmHg) in the intervention group and non-treatment in the control group.

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This S2k guideline was developed on the initiative and under the German Society of Phlebology and Lymphology (DGPL) leadership. The guideline aims to optimize the diagnosis and treatment of lipedema. It is intended to bring together the different approaches of the respective professional groups in a consensus-based manner and thus offer a basic concept for the best possible treatment of patients with lipedema.

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Article Synopsis
  • - The S2k guideline on venous leg ulcers was developed by a collaborative group led by the German Society of Phlebology and Lymphology, including various other German medical societies.
  • - The goal is to unify different medical approaches to create a comprehensive treatment framework for venous leg ulcers, benefiting both patients and healthcare professionals.
  • - It includes 70 specific recommendations across key areas like diagnostics, therapy, prevention of recurrences, and everyday challenges, reflecting the latest scientific knowledge for clinical practice.
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Objective: The aim of this study was to assess the utilization of surgical interventions in patients diagnosed with superficial vein thrombosis (SVT) and its potential association with the occurrence of venous thromboembolism (VTE) and bleeding events.

Methods: INSIGHTS-SVT, a prospective, non-interventional, multicenter study in Germany, investigated the management and outcomes of patients with acute SVT who received conservative and/or invasive treatments at the discretion of the treating physician.

Results: Among the 872 patients with 12-month data, 657 had medical therapy only, and 215 patients underwent vascular surgery (70 within 3 months of SVT diagnosis, 136 between months 4 and 12, and nine had an intervention in both periods).

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  • Diuretics are commonly used in neonatal wards, despite little proof of effectiveness for several conditions, prompting a study on their use rates in a multicenter French cohort.
  • An observational study included 86,032 neonates, finding an overall diuretic exposure rate of 8.5%, with significant variation across different medical centers (2.4% to 26.5%).
  • The main drugs used were furosemide, spironolactone, and dopamine, often prescribed for fluid retention, but practices differed among centers, sometimes exceeding safe dosage and treatment duration limits.
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