Publications by authors named "E Rabaiotti"
Background: Pregnancy associated breast cancer is the most common cancer diagnosed during pregnancy. When chemotherapy is indicated, although it is more common to use anthracycline-based chemotherapy as a first treatment, we suggest weekly paclitaxel as a valid alternative both in the adjuvant and neoadjuvant setting, as this allows for weekly assessment of maternal-fetal well-being and a quicker maternal and fetal bone marrow recovery in cases of unexpected preterm delivery.
Patients And Methods: We present a case series of pregnant breast cancer patients treated with weekly paclitaxel between 2016 and 2022.
Article Synopsis
- Immunotherapy shows limited benefits for patients with epithelial ovarian cancer (EOC), highlighting the need to better understand local immune dynamics and pathways that suppress T-cell activity against tumors.
- The study analyzed tumor samples from 48 EOC patients to investigate the immune cell composition, focusing on tumor-infiltrating lymphocytes (TILs) using various research methods.
- Findings revealed a unique population of activated T cells in EOC tumors and identified the role of macrophages in both stimulating and inhibiting immune responses, suggesting potential targets for improving immunotherapy efficacy.
Evidence indicates that different pathways of malignant degeneration underlie the development of endometriosis-associated ovarian tumors of endometrioid and clear cell histotypes. The aim of this study was to compare data from patients affected by these two histotypes to investigate the hypothesis of a dichotomy in the histogenesis of these tumors. Clinical data and tumor characteristics of 48 patients who were diagnosed with either pure clear cell ovarian cancer and mixed endometrioid-clear cell ovarian cancer arising from endometriosis (ECC, = 22) or endometriosis-associated endometrioid ovarian cancer (EAEOC, = 26) were compared.
View Article and Find Full Text PDFCancer patients are at an increased risk of developing severe consequences due to the COVID-19 infection. However, psychological outcomes in this population have been overlooked in the literature. The present study aims to identify significant psychological differences between gynecological cancer patients undergoing chemotherapy before and during the pandemic.
View Article and Find Full Text PDFRadiotherapy has been increasingly considered as an active treatment to combine with other approaches (i.e., surgery, chemotherapy, and novel target-based drugs) in ovarian cancers to palliate symptoms and/or to prolong chemotherapy-free intervals.
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