Publications by authors named "E RIZZOLI"
Article Synopsis
- * In research using a mouse model that mimics ARO, gene therapy (GT) with lentiviral vectors effectively improved bone density and allowed for long-term survival, while also enhancing the collection of necessary stem cells through a method called plerixafor-induced mobilization.
- * The study suggests that non-genotoxic conditioning before transplantation can lead to better outcomes, including stable stem cell engraftment and improved bone health, providing a
Article Synopsis
- Canine idiopathic pulmonary fibrosis (CIPF) is a serious lung disease primarily affecting elderly West Highland white terriers and is linked to respiratory failure, with unknown causes.
- * The study aimed to assess the expression of fibroblast activation protein (FAP) in lung biopsies from CIPF-infected dogs and evaluate its potential as a biomarker for fibrosis activity.
- * Results showed that while FAP levels were low in the blood of affected dogs, FAP expression was significantly higher in lung tissues with active fibrosis, suggesting its role in monitoring disease severity.
Plant sterols are well-known natural lipid-lowering agents. The DESCO (Diet and plant sterols in the control of cholesterolemia) study was a single-center, randomized, double-blind, placebo-controlled, two-way crossover clinical trial designed to investigate the effect of a once-a-day ready-to-drink dietary supplement containing 2.5 g of phytosterols on the lipid profile, also in relation to the quality of the diet, in a cohort of 50 Italian individuals with polygenic hypercholesterolemia and low global cardiovascular risk.
View Article and Find Full Text PDFIntroduction: In addition to healthy lifestyle and balanced diet, nutraceutical supplementation may be useful to maintain overall metabolic wellness. The aim of the present study was to assess the metabolic and vascular effects of a new, highly standardized bergamot phytocomplex supplement in healthy volunteers with the features of metabolic syndrome.
Material And Methods: We carried out a double-blind, randomized, placebo-controlled, three-arm, parallel-group clinical trial in 90 adult subjects (30 per group) treated for 12 weeks with two different dosages of a highly standardized bergamot phytocomplex (Endoberg by AKHYNEX and Kalita by Giellepi) or placebo.
Even though coffee consumption has been clearly related to a number of benefits to the cardiovascular system, its effect on blood pressure (BP) has not been fully elucidated. In this sub-analysis of the Brisighella Heart Study (BHS), we compared central and peripheral BP values in a sub-cohort of 720 men (47.9%) and 783 women (52.
View Article and Find Full Text PDF