Publications by authors named "E R Trumble"

Background: Brain intraparenchymal schwannoma is a rare clinical entity, generally curable with adequate resection.

Methods And Results: We describe a case in a male patient first presenting at 19 months of age, the youngest reported age for this lesion. It also appears to be the first case connected to a germline TSC2 p.

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Purpose: Germinal matrix hemorrhage/intraventricular hemorrhage (GMH-IVH) affects primarily preterm infants and causes significant morbidity and mortality. Health disparities are a reality for underserved populations, such as those rural patients. As our institution serves a substantial portion of rural patients, we examined mortality rates and rates of permanent cerebrospinal fluid (CSF) diversion in newborns with GMH-IVH.

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Rosai-Dorfman disease (RDD) with craniocervical junction involvement is a rare clinical entity. We present herein a case of a pediatric patient with craniocervical junction RDD which was surgically treated. A 10-year-old female with a history of B-cell acute lymphoblastic leukemia (B-ALL) in remission and RDD presented with frontal migraine headaches.

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To determine the effect of distributed practice (spacing out of study over time) and retrieval practice (recalling information from memory) on academic grades in health professions education and to summarise a range of interventional variables that may affect study outcomes. A systematic search of seven databases in November 2022 which were screened according to predefined inclusion criteria. The Medical Education Research Study Quality Instrument (MERSQI) and Newcastle-Ottawa Scale-Education (NOS-E) were used to critically appraise eligible articles.

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Article Synopsis
  • The 2021 WHO Classification of Tumors of the Central Nervous System introduced new insights on the role of oncohistones in glioma development, notably adding the H3.3-G34R/V mutant glioma alongside the already recognized H3-K27M altered glioma.
  • Despite advancements in understanding these tumors, the prognosis for patients remains poor, with limited research specifically targeting the understudied H3.3-G34R/V mutant glioma population.
  • The review aims to summarize the current knowledge on the molecular mechanisms involved in H3.3-G34R/V mutant gliomas, as well as information regarding their diagnosis, treatment, long-term outcomes, and potential future therapies.
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