Parallel randomised trial testing community fibrosis assessment for suspected non-alcoholic fatty liver disease: outcomes from LOCATE-NAFLD.

Objective: Non-alcoholic fatty liver disease (NAFLD) is estimated to affect a third of Australian adults, and its prevalence is predicted to rise, increasing the burden on the healthcare system. The LOCal Assessment and Triage Evaluation of Non-Alcoholic Fatty Liver Disease (LOCATE-NAFLD) trialled a community-based fibrosis assessment service using FibroScan to reduce the time to diagnosis of high-risk NAFLD and improve patient outcomes.

Methods: We conducted a 1:1 parallel randomised trial to compare two alternative models of care for NAFLD diagnosis and assessment.

An annotated biobank of triple negative breast cancer patient-derived xenografts featuring treatment-naïve and longitudinal samples throughout neoadjuvant chemotherapy.

Triple negative breast cancer (TNBC) that fails to respond to neoadjuvant chemotherapy (NACT) can be lethal. Developing effective strategies to eradicate chemoresistant disease requires experimental models that recapitulate the heterogeneity characteristic of TNBC. To that end, we established a biobank of 92 orthotopic patient-derived xenograft (PDX) models of TNBC from the tumors of 75 patients enrolled in the ARTEMIS clinical trial ( NCT02276443 ) at MD Anderson Cancer Center, including 12 longitudinal sets generated from serial patient biopsies collected throughout NACT and from metastatic disease.

Barbenigma Powell & Miller, a bizarre new genus and two new species of scale insects (Hemiptera: Coccomorpha: Ortheziidae) from the United States.

A strange new genus and two species of scale insect from the United States, Barbenigma Powell & Miller, gen. nov. and Barbenigma biza Powell & Miller, sp.

Three new species of Puto giant mealybugs (Hemiptera: Coccomorpha: Putoidae) from Mexico and Guatemala, with keys to New World adult females and World adult males.

Three new species of Puto Signoret, 1876 are described and illustrated from material intercepted at US plant quarantine inspection, including the adult females, all available immature stages, and for two species, the adult male. Puto philo Powell & Miller, sp. n.

Validation of a Training Model for Austere Veno-Venous Extracorporeal Membrane Oxygenation Cannulation and Management.

Introduction: Veno-venous extracorporeal membrane oxygenation (VV ECMO) is used in trauma patients with pulmonary injury in the acute setting. The United States Military has an advanced ECMO transport and management capability; however, future conflicts may require forward prolonged casualty care (PCC). Special Operations Surgical Teams (SOSTs) provide damage control surgery, resuscitation, and PCC in forward, unregulated, multidomain environments.