Acta Odontol Scand
January 2023
Objective: This study aimed to evaluate whether ligature-induced periodontitis and rheumatoid arthritis (RA) potentiate the deleterious effects on functional capacity, periodontal and synovial tissues, leukocyte migration, and interleukin 17 (IL-17) levels, and to investigate the repercussions of single Freund's Complete Adjuvant (FCA) injection associated with periodontitis.
Materials And Methods: Fifty-one male rats were randomised into six groups: control (CG, = 8), RA (RAG, = 9), periodontitis (PG, = 9), periodontitis and RA (PRAG, = 9), periodontitis and intradermal injection (PIDG, = 9), and periodontitis and intra-articular injection (PIAG, = 7). The animals underwent ligature placement and one or two injections with FCA to induce RA.
Forty Wistar rats were used: (1) control group (CG); (2) group of periodontal disease (PD); (3) type 1 diabetes mellitus group (T1DM); (4) type 1 diabetes mellitus + periodontal disease group (T1DM + PD). In groups T1DM and T1DM + PD, T1DM induction was performed with the administration of streptozotocin (STZ) 80 mg/kg intraperitoneal body weight. The PD and T1DM + PD groups were submitted to PD induction with ligation.
View Article and Find Full Text PDFPeriodontal disease is considered a public health problem because of its high prevalence, while premature birth is a serious perinatal problem, persisting as one of the major causes of perinatal mortality and morbidity. Therefore, the objective of this study was to evaluate the effect of maternal periodontal disease on the occurrence of preterm birth and the birth weight of their babies. The study sample included 45 new mothers, aged 18-35 years, who presented either slight or moderate to severe localized or generalized chronic periodontitis with bleeding on probing and gingival inflammation.
View Article and Find Full Text PDFAnimals (Basel)
November 2019
This project determined how neural circuits are affected during warming by examining sensory neurons, the neuromuscular junction, and the cardiac function and behavior of the commercially important crustacean species, the red swamp crayfish ( ). Rapid inactivation of neural function in crustaceans prior to slaughter is important to limit exposure to noxious stimuli, thus improving animal welfare. This study demonstrated that as a crayfish is warmed at 1 °C/min, the heart beat stops at 44 °C.
View Article and Find Full Text PDFStunning of edible crustaceans to reduce sensory perception prior and during slaughter is an important topic in animal welfare. The purpose of this project was to determine how neural circuits were affected during stunning by examining the physiological function of neural circuits. The central nervous system circuit to a cardiac or skeletal muscle response was examined.
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