Perioperative transfusion management in craniotomies: A national survey, a starting point for the evaluation of improvements in health care.

Objective: To assess the perioperative management of haemostasis and transfusion practices in adult patients undergoing craniotomies.

Method: Online questionnaire addressed to Spanish anaesthesiologists and promoted by the Neurosciences and Haemostasis, Transfusion Medicine and Fluid Therapy Sections of SEDAR. The questionnaire was sent by email and social media, and was active between June and October 2022.

Predicting the replicability of social and behavioural science claims in COVID-19 preprints.

Replications are important for assessing the reliability of published findings. However, they are costly, and it is infeasible to replicate everything. Accurate, fast, lower-cost alternatives such as eliciting predictions could accelerate assessment for rapid policy implementation in a crisis and help guide a more efficient allocation of scarce replication resources.

Exploring Stigma Towards People with Schizophrenia in Mass Media and Their Private Discourses.

Introduction: It has been shown that public stigma towards people with schizophrenia hinders their psychosocial integration. Public stigma expresses itself through lexical labels used in the print media and social networks, heightening the internalization of stigma in this population, a phenomenon known as internalised stigma or self-stigma. This paper analyses the diffusion in the mass media of two dimensions of stigma: public stigma and self-stigma.

Surface Modification of Gold Nanorods (GNRDs) Using Double Thermo-Responsive Block Copolymers: Evaluation of Self-Assembly and Stability of Nanohybrids.

A series of copolymers containing a thermo-responsive biocompatible first block of poly[di(ethylene glycol) methyl ether methacrylate)--(oligo(ethylene glycol) methyl ether methacrylate], P(DEGMA--OEGMA) were chain-extended to incorporate either poly(-isopropylacrylamide), PNIPAAm or poly(-isopropylacrylamide--butyl acrylate), P(NIPAAm-co-BA) as second thermo-responsive block using reversible addition-fragmentation chain transfer (RAFT) polymerization. P(DEGMA--OEGMA)--PNIPAAm copolymers showed two response temperatures at 33 and 43 °C in an aqueous solution forming stable aggregates at 37 °C. In contrast, P(DEGMA--OEGMA)--P(NIPAAm--BA) copolymers showed aggregation below room temperature due to the shift in response temperature provoked by the presence of hydrophobic butyl acrylate (BA) units, and shrinkage upon heating up to body temperature, while maintaining the second response temperature above 40 °C.

Proton quantal delocalization and H/D translocations in (MeOH)nH+ (n = 2, 3).

In this study, we present results from path integral molecular dynamics simulations that describe the characteristics of the quantum spatial delocalizations of protons participating in OH bonds in (MeOH)2H+ and in (MeOH)3H+. The characterization was carried out by examining the overall structures of the corresponding isomorphic polymers. To introduce full flexibility in the force treatment, we have adopted a neural network fitting procedure based on second-order Møller-Plesset perturbation theory predictions.