[The Karachi health resort: synthesis of science and practice].

This article is devoted to the history of one of the oldest Siberian health resorts known as "The Karachi Lake". It describes the stages of its development, the scientific component of the system of spa-and-resort therapy and medico-social rehabilitation of the patients. The detailed analysis of the mechanisms underlying the beneficial action of the natural therapeutic factors, cooperation with the leading research institutions, and the formation of the modern scientific and technical basis have strengthened the position of the resort on the market of the medical, health-promoting, and recreational services due to the development of the new activities in this field.

[The chronobiological peculiarities of the hepatobiliary system function in chronic cholecystitis with dysfunction of the gallbladder].

Study of biological cycles in chronic cholecystitis with dysfunction of gallbladder has a great practical importance. The results of chronoanalysis testify a dominance of 24-hours cycle in structure of cycles of functional activity of organs of hepatobiliary system. The comparative analysis of trust intervals reveals the intensification of internal connections, expressed intensification of synchronization of cycles of functional activity of system and a breach of synchronism of central regulation and self-regulation, testifying overstrain of proper adaptive possibilities and unconcordance in system of regulation.

[The application of UHF therapy for the prevention of complications of specific antiblastoma therapy in the patients presenting with III-IV stage lung cancer].

One of the complications of specific antiblastoma therapy in the patients presenting with malignant neoplasms is the suppressed functional activity of blood neutrophil granulocytes. The results of clinical and experimental investigations suggest the enhanced enzymatic activity of neutrophils and lymphocytes under effect of ultrahigh-frequency electromagnetic radiation (UHF EMR). Our study has demonstrated that UHF EMR with a frequency selected on an individual basis in the range from 59 to 63 GHz exerts the protective action on the function and metabolism of blood neutrophils exposed to the damaging action of gamma-radiation in the patients presenting with lung cancer.

[The development of medical technologies for the spa and resort rehabilitation of patients presenting with pathology of the biliary system taking into consideration circumannual biorhythms].

This study included 188 patients presenting with pathology of the biliary system, such as dyskinesia of bile ducts, chronic non-calculous cholecystitis (CCC), and dysfunction of the bile system. The objective of the work was to develop complexes of intensive non-medicamental rehabilitative treatment for the correction of the adaptive potential of the organism in the springtime (March-May). It was shown that the efficacy of therapy during this period can be improved by modulation of the complex structure.

[Circumannular features of non-specific resistance in patients with osteoarthrosis in mid-lattitudes].

Modified cosinor-analysis was used to calculate biorhythmologic characteristics (period, amplitude, phase, mesor) of the circumannual rhythm of neuroendocrine regulation parameters, the state of bioradical hemostasis, and protein components of non-specific resistance in patients with osteoarthrosis living in moderate climates. Near-annual rhythms of these parameters are described. The chronological analysis indicates that strenuouos activity of the regulatory systems responsible for adaptive reactions of the organism falls within the periods from March to May and from August to October.