Publications by authors named "E R Guinto"
Article Synopsis
- - A study created a detailed map of the airway cells in patients with pulmonary long COVID, focusing on those who have persistent respiratory symptoms after a COVID-19 infection.
- - Participants with long COVID were compared to those whose symptoms had resolved or who had never been infected, with analysis revealing unique neutrophil clusters in the long COVID group.
- - The findings suggest that increased inflammation and changes in airway cell function, particularly involving neutrophils, may be responsible for the lingering respiratory issues seen in long COVID patients.
Importance: Endometriosis has been associated with an increased risk of ovarian cancer; however, the associations between endometriosis subtypes and ovarian cancer histotypes have not been well-described.
Objective: To evaluate the associations of endometriosis subtypes with incidence of ovarian cancer, both overall and by histotype.
Design, Setting, And Participants: Population-based cohort study using data from the Utah Population Database.
Purpose: The purpose of this study was to determine whether there is an increased risk of mortality among individuals with keratoconus.
Methods: This was a retrospective, case-control study using the Utah Population Database. Cases were defined as individuals diagnosed with keratoconus from 1996 to 2020 and were matched 5:1 with controls on birth year, sex, whether born in Utah, and follow-up time in Utah.
Single-cell RNA sequencing (scRNA-seq) is an important tool for understanding disease pathophysiology, including airway diseases. Currently, the majority of scRNA-seq studies in airway diseases have used invasive methods (airway biopsy, surgical resection), which carry inherent risks and thus present a major limitation to scRNA-seq investigation of airway pathobiology. Bronchial brushing, where the airway mucosa is sampled using a cytological brush, is a viable, less invasive method of obtaining airway cells for scRNA-seq.
View Article and Find Full Text PDFBackground: A proportion of coronavirus disease 2019 (COVID-19) survivors experience persistent dyspnoea without measurable impairments in lung function. We performed a systematic review and meta-analysis to determine relationships between dyspnoea and imaging abnormalities over time in post-COVID-19 patients.
Methods: Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we analysed studies published prior to 15 September 2022 and indexed by Google Scholar, PubMed and LitCOVID which assessed chest imaging in adults ≥3 months after COVID-19.