Publications by authors named "E R Ferre"
The dimensions of objects and our body parts influence our perception of the weight of objects in our surroundings. It has been recently described a dramatic underestimation of the perceived weight of the hand. However, little is known on how perceived size informs the perceived weight of our own body parts.
View Article and Find Full Text PDFResearch on media's effects on body perception has mainly focused on the role of vision of extreme body types. However, haptics is a major part of the way children experience bodies. Playing with unrealistically thin dolls has been linked to the emergence of body image concerns, but the perceptual mechanisms remain unknown.
View Article and Find Full Text PDFArticle Synopsis
- APECED is a serious genetic autoimmune disorder linked to variants in the autoimmune regulator (AIRE) gene, with 16% of evaluated patients lacking known harmful variants, most of whom are of Puerto Rican descent.
- Researchers discovered a deep intronic variant (c.1504-818 G>A) in these patients that causes a cryptic splice site leading to a dysfunctional protein through pseudoexon inclusion.
- They developed an antisense oligonucleotide (ASO) that corrected this genetic issue, demonstrating the potential for targeted treatments in APECED patients.
Emicizumab is a bispecific antibody that mimics the function of factor VIII (FVIII) and is indicated for prophylactic use in patients with congenital hemophilia A with or without inhibitors. Acquired hemophilia A (AHA) is a rare and severe disorder causes by autoantibodies that inhibit FVIII. In AHA, acute bleeding are managed with bypassing agents but several reports described the off-label use of emicizumab.
View Article and Find Full Text PDFArticle Synopsis
- Cutaneous protothecosis is an uncommon infection that affects the skin and can spread systemically, requiring long-term treatment with medications that may have harmful side effects.
- The case study focuses on a patient whose skin infection did not respond to standard triazole treatment.
- The patient showed significant improvement after being treated with a new oral formulation of amphotericin B, which was effective without causing any toxicity.