Z Gerontol
December 1983
From the therapeutical point of view, reliable differentiations of different dementia types are required. Electrophysiological methods could be advantageous for this purpose. Healthy elderly people already show slight EEG-changes as slower alpha rhythm with decreased percent time and amplitude, furtheron temporal foci predominantly on the left side.
View Article and Find Full Text PDFArzneimittelforschung
January 1981
A review on the clinical properties of sulpiride (Dogmatil forte) which up to the present day are yet accepted unanimously is presented. By means of visually evoked potentials (VEP) a study was carried out in 25 schizophrenic patients during an observation period of 24 days. The analysis of amplitudes and latencies of VEPs with dosages from 200 mg/day up to 1200 mg/day showed that low doses (200 mg/day) have a thymoleptic VEP profile, similar to that of amitriptyline, whereas dosages of 600--1200 mg/day show a medium to strong neuroleptic action, similar in its VEP profile to those of perphenazine and fluphenazine.
View Article and Find Full Text PDFThe paper describes a study of visually evoked potentials (VEP) during 50 days in a schizophrenic female patient to whom we administered increasing dosages (from 150 mg up to 600 mg) and afterwards progressively decreasing ones (from 600 mg to 20 mg) of 10-(3-[4-(2-hydroxyethyl)-1-piperazinyl]-propyl)-2-trifluoromethylphenothiazine (fluphenazine-dihydrochloride). We tried to establish a relation between the aspect of latencies and form of curves and the dosages. We also discussed a possible correspondence between VEP and psychopathological changes.
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