Publications by authors named "E R BROSTEANU"

From the therapeutical point of view, reliable differentiations of different dementia types are required. Electrophysiological methods could be advantageous for this purpose. Healthy elderly people already show slight EEG-changes as slower alpha rhythm with decreased percent time and amplitude, furtheron temporal foci predominantly on the left side.

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A review on the clinical properties of sulpiride (Dogmatil forte) which up to the present day are yet accepted unanimously is presented. By means of visually evoked potentials (VEP) a study was carried out in 25 schizophrenic patients during an observation period of 24 days. The analysis of amplitudes and latencies of VEPs with dosages from 200 mg/day up to 1200 mg/day showed that low doses (200 mg/day) have a thymoleptic VEP profile, similar to that of amitriptyline, whereas dosages of 600--1200 mg/day show a medium to strong neuroleptic action, similar in its VEP profile to those of perphenazine and fluphenazine.

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The paper describes a study of visually evoked potentials (VEP) during 50 days in a schizophrenic female patient to whom we administered increasing dosages (from 150 mg up to 600 mg) and afterwards progressively decreasing ones (from 600 mg to 20 mg) of 10-(3-[4-(2-hydroxyethyl)-1-piperazinyl]-propyl)-2-trifluoromethylphenothiazine (fluphenazine-dihydrochloride). We tried to establish a relation between the aspect of latencies and form of curves and the dosages. We also discussed a possible correspondence between VEP and psychopathological changes.

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