Publications by authors named "E Quintana-Gallego"

Background: Cystic fibrosis (CF) patients are prone to recurrent multi-drug-resistant (MDR) bacterial lung infections. Under this scenario, phage therapy has been proposed as a promising tool. However, the limited number of reported cases hampers the understanding of clinical outcomes.

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Article Synopsis
  • There is significant confusion regarding the correct dosage of inhaled medications, prompting a review of inhalation therapy devices.
  • A systematic search identified 90 unique inhalation products, noting variations in long-acting bronchodilators and inhaled corticosteroids, with different marketing practices for dosages.
  • The findings indicate that each inhaled drug may have multiple dosage forms, emphasizing the need for clinicians to be cautious when prescribing these medications.
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Introduction: Elexacaftor/tezacaftor/ivacaftor (ETI) was used through the early access programme in Spain from December 2019 in cystic fibrosis (CF) patients with homozygous or heterozygous F508del mutation with advanced lung disease.

Methodology: Multicentre, ambispective, observational, study in which 114 patients in follow-up in 16 national CF units were recruited. Clinical data, functional tests, nutritional parameters, quality of life questionnaires, microbiological isolates, number of exacerbations, antibiotic treatments and side effects were collected.

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