Publications by authors named "E Quevillon"
During 2015-2016, we evaluated the performance of whole-genome sequencing (WGS) as a routine typing tool. Its added value for microbiological and epidemiologic surveillance of listeriosis was compared with that for pulsed-field gel electrophoresis (PFGE), the current standard method. A total of 2,743 Listeria monocytogenes isolates collected as part of routine surveillance were characterized in parallel by PFGE and core genome multilocus sequence typing (cgMLST) extracted from WGS.
View Article and Find Full Text PDFtcf (Typhi colonization factor) is one of the 12 putative chaperone/usher fimbrial clusters present in the Salmonella enterica serovar Typhi genome. We investigated the production, expression and regulation of tcf as well as its role during interaction with human cells. The tcf gene cluster was cloned and induced in Escherichia coli and S.
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- Bovine tuberculosis (bTB) poses significant economic and public health challenges, impacting livestock management and health in nonindustrialized regions, and is influenced by specific immune responses.
- The study analyzed peripheral blood cells in cattle with varying immune responses (seropositive and seronegative for M. bovis) using flow cytometry and found notable differences, particularly a decrease in CD8(+) T cells and an increase in B cells within the seropositive group.
- Both seropositive and seronegative cattle displayed heightened cellular activation when exposed to bovine purified protein derivative and showed increased leukocyte counts compared to healthy controls, indicating altered immune responses related to bTB infection.
Sclerotinia sclerotiorum and Botrytis cinerea are closely related necrotrophic plant pathogenic fungi notable for their wide host ranges and environmental persistence. These attributes have made these species models for understanding the complexity of necrotrophic, broad host-range pathogenicity. Despite their similarities, the two species differ in mating behaviour and the ability to produce asexual spores.
View Article and Find Full Text PDFLymphocyte transformation induced by Theileria parasites involves constitutive activation of c-Jun N-terminal kinase (JNK) and the AP-1 transcription factor. We found that JNK/AP-1 activation is associated with elevated levels of Rab11 protein in Theileria-transformed B cells. We show that AP-1 regulates rab11a promoter activity in B cells and that the induction of c-Jun activity in mouse fibroblasts also leads to increased transcription of the endogenous rab11a gene, consistent with it being an AP-1 target.
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