Respiratory Effects of Maximal Lung Recruitment Maneuvers Using Single-Breath Estimation in ARDS.

Background: Determining which patients with ARDS are most likely to benefit from lung recruitment maneuvers is challenging for physicians. The aim of this study was to assess whether the single-breath simplified decremental PEEP maneuver, which evaluates potential lung recruitment, may predict a subject's response to lung recruitment maneuvers, followed by PEEP titration.

Methods: We conducted a pilot prospective single-center cohort study with a 3-step protocol that defined sequential measurements.

Beached seabirds as plastic biomonitors in Brazil from the Beach Monitoring Project of the Santos Basin (PMP-BS).

Bioindicator species are useful to monitor wildlife exposure to plastic pollution, and responses to plastic leakage and policy interventions. Here we explore the biomonitoring potential of different seabird and shorebirds species across six years of monitoring in Brazil. Using the necropsy stranding database of the Beach Monitoring Project of the Santos Basin (PMP-BS), we evaluated i) the frequency of birds-plastic interactions in Brazil; ii) whether plastic interactions have changed through time and in different coastal regions; and iii) potential bioindicators for monitoring the exposure of seabirds to plastic in the nearshore South Atlantic Ocean.

The use of health geography modeling to understand early dispersion of COVID-19 in São Paulo, Brazil.

Public health policies to contain the spread of COVID-19 rely mainly on non-pharmacological measures. Those measures, especially social distancing, are a challenge for developing countries, such as Brazil. In São Paulo, the most populous state in Brazil (45 million inhabitants), most COVID-19 cases up to April 18th were reported in the Capital and metropolitan area.