Publications by authors named "E Prevete"

Rationale: Despite the growing scientific interest on mitragynine, the primary alkaloid in kratom (Mitragyna Speciosa), there is a lack of clinical trials in humans.

Objectives: This phase 1 study aimed to evaluate mitragynine's safety profile and acute effects on subjective drug experience, neurocognition, and pain tolerance.

Methods: A placebo-controlled, single-blind, within-subjects study was conducted in two parts.

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Objective: Reciprocal connections exist between mental health and physical health, and conditions of cellular senescence/advanced biological age have been observed in association with certain psychiatric diseases. However, the construct of frailty has only preliminarily been explored in young adults and in relation to psychopathology so far. In the present study we aimed at further elucidating the relationships linking psychopathological phenomena with physical diseases in a sample of young adults.

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Article Synopsis
  • * A bibliometric analysis of Captagon literature reveals a focus on its impact in conflict zones, with increasing research contributions from Saudi Arabia, Jordan, and Iraq, highlighting the need for more studies on its mechanisms and risks.
  • * Major gaps in understanding Captagon's effects and management strategies exist, indicating the need for further research to develop effective interventions and public health policies.
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Article Synopsis
  • The study investigates Problematic Use of Internet (PUI) and its relationship to mental health issues among 143 psychiatric outpatients, finding that the prevalence of PUI ranges from 1% to 25% depending on the assessment tool used.
  • Results indicate that PUI is significantly associated with age, and higher in students, with correlations to personality and eating disorders, as well as other addictions like alcohol and substance use.
  • The authors suggest further research on PUI among students and endorse the need for awareness among healthcare providers and educators about the risks linked to PUI and its potential shared pathophysiology with other addiction disorders.
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Objective: Obsessive and compulsive symptoms (OCS) are cross-cutting psychopathological manifestations frequently detected in a variety of clinical and non-clinical samples. It has been suggested that impaired mentalization abilities and traumatic experiences during childhood may be relevant etiopathogenetic factors in the development of OCS. The purpose of the current study was to cross-sectionally assess these variables in a non-clinical sample, testing the mediational role of mentalization abilities in the association between childhood trauma (CT) and OCS.

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