Publications by authors named "E Pouchol"
Background And Objectives: In 2016, France allowed men who have sex with men (MSM) to donate blood if they had not had sex with men in the previous 12 months. In April 2020, this restriction was relaxed to 4 months due to the lack of negative impact observed on blood safety. This study assesses the impact of reducing this deferral period on epidemiological surveillance indicators.
View Article and Find Full Text PDFArticle Synopsis
- Syphilis cases among blood donors in France have been rising, with a significant uptick observed in 2022 compared to earlier years.
- Data from over 45 million donations (2007-2022) revealed that the infection rate was notably higher in males, particularly among men who have sex with men (MSM), whose risk factor percentage increased over time.
- A non-treponemic test (NTT) was used to assess infection recency, but the data were insufficient to reliably differentiate between recent and past infections among the syphilis-positive donors.
Background And Objectives: Pathogen reduction (PR) technology may reduce the risk of transfusion-transmitted infections (TTIs), notably transfusion-transmitted bacterial infection (TTBI) associated with platelet concentrates (PCs). PR (amotosalen/UVA treatment) was implemented for all PCs transfused in France in November 2017. No bacterial detection was in place beforehand.
View Article and Find Full Text PDFBackground And Objectives: Data from 21 years (2000-2020) of haemovigilance were used to assess human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) incidence rates in repeat blood donors and the occurrence of transfusion-transmitted (TT) viral infections.
Materials And Methods: Blood donors who converted for HIV, HCV or HBV markers within serial three-year analysis periods were included. Epidemiological and virological data were retrieved from the national epidemiological donor database and were supplemented with information on blood components and the infection status of recipients of the previous negative donation (D.
Hepatitis E has emerged as a major transfusion-transmitted infectious risk. Two recipients of plasma from 2 lots (A and B) of pooled solvent/detergent-treated plasma were found to be infected by hepatitis E virus (HEV) that was determined to have been transmitted by the solvent/detergent-treated plasma. HEV RNA viral loads were 433 IU in lot A and 55 IU in lot B.
View Article and Find Full Text PDF