Antipyretic activity of N-acetylcysteine.

N-acetylcysteine (NAC) has been used primarily as a mucolytic agent for the treatment of respiratory diseases. It has been recently suggested that NAC also possesses some anti-inflammatory properties. The aim of the present study is to investigate the effects of NAC on fever provoked either by bacterial lipopolysaccharide (LPS) or a turpentine-induced aseptic abscess in the rats.