Publications by authors named "E Pompe"

Article Synopsis
  • Chronic obstructive pulmonary disease (COPD) has been linked to small vessel abnormalities, contributing to increased mortality, but their specific impact is still unclear.
  • In a study involving 7,903 individuals, researchers analyzed small artery and vein dimensions and found that high volumes of both were independently associated with increased mortality rates.
  • The findings suggest that abnormal small vessel sizes in smokers are significant for mortality risk, highlighting the need for further research into the causes and effects of these vascular changes.
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Introduction: Differences in body composition in patients with COPD may have important prognostic value and may provide opportunities for patient-specific management. We investigated the relation of thoracic fat and muscle with computed tomography (CT)-measured emphysema and bronchial wall thickening.

Methods: Low-dose baseline chest CT scans from 1031 male lung cancer screening participants from one site were quantified for emphysema, bronchial wall thickening, subcutaneous fat, visceral fat and skeletal muscle.

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Asthma is a common disorder affecting around 315 million individuals worldwide. The heterogeneity of asthma is becoming increasingly important in the era of personalized treatment and response assessment. Several radiological imaging modalities are available in asthma including chest x-ray, computed tomography (CT) and magnetic resonance imaging (MRI) scanning.

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Background: Little is known about factors associated with emphysema progression in cigarette smokers. We evaluated factors associated with change in emphysema and forced expiratory volume in 1 second (FEV) in participants with and without chronic obstructive pulmonary disease (COPD).

Methods: This retrospective study included individuals participating in the COPD Genetic Epidemiology study who completed the 5-year follow-up, including inspiratory and expiratory computed tomography (CT) and spirometry.

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