Comparison of tin and lead toxic action on erythropoietic system in blood and bone marrow of rabbits.

The aim of this work was to assess and compare morphological changes in blood and bone marrow of rabbits after per os (po) or intraperitoneal (ip) administration of equimolar doses of tin or lead. The experiment was performed on female rabbits that were divided into four groups of six animals each, and received stannous chloride SnCl2 x 2 H2O (Merck) or lead acetate Pb(CH3COO)2 (POCh Gliwice) in equimolar doses (ip--17/microM/kg) or per os (po--85/microM/kg). Group I was administered SnCl2 ip at the dose of 2 mg Sn/kg every day for 3 mo, group II Pb(CH3COO)2 ip at a dose of 3.

[Acute nonlymphoblastic leukemia as a secondary malignancy--demonstration of 15 patients].

Among 90,128 patients with malignancies in the years 1976-1989 acute non lymphoblastic leukaemia (ANLL) was diagnosed in 351 patients (0.4%) and in 15 (4.3%) of them ANLL was secondary neoplasm.

[Ferritin levels in blood serum and mononuclear cells of peripheral blood in lymphatic neoplasms of low and medium degrees of malignancy].

Ferritin levels in blood serum and mononuclear cells of the peripheral blood were determined in 60 patients with chronic lymphatic leukemia (group I), and 31 patients with other lymphomas of the low and medium degree of malignancy (group II). Significantly higher blood serum and mononuclear cells ferritin was found in the examined patients than in 54 healthy individuals. Particularly high ferritin levels were seen in blood serum of patients of group II in whom clinical stage of the disease was high.

[Disorders of lipid and lipoprotein metabolism in patients with chronic lymphocytic leukemia. I. Preliminary evaluation of lipemia and HDL fractions in various stages of the disease].

The study comprised 128 patients with chronic lymphocytic leukemia (CLL) aged 65.7 +/- 8 years, 59 women and 69 men. Among the patients studied 70 were treated and 58 yet not underwent therapy.

The coexistence of chronic lymphocytic leukaemia and polycythaemia vera terminating in acute myeloid leukaemia.

A 67-year-old man with the coexistence of CLL and PV converted after 4 years to AML is described. This rare simultaneous occurrence of both chronic lymphoid and myeloid proliferations as well as nonlymphoblastic leukaemia developing in a patient with CLL is discussed in the light of literature data.