Publications by authors named "E Pizarro Orchard"

Objective: The risk of aortic dissection is increased in Turner Syndrome (TS). Aortic dilation is thought to contribute to this risk and may be managed with elective aortic surgery. New TS guidance has lowered the aortic size thresholds for consideration of aortic surgery.

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Introduction: Cardiovascular disease is the most common cause of death in Turner syndrome (TS) for which arterial hypertension has a direct influence and is a key modifiable risk factor.

Objective: To investigate the prevalence and patterns of hypertension diagnosis and management in adult patients with TS who are registered in a large international multicentre database (TS-HTN study).

Methods: Retrospective multicentre observational study of patients aged ≥18 years included in the I-TS (International-TS) registry (2020-2022), using registry and participating centre-collected data.

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Background: On-scene improvised and interim decontamination protocols in the Initial Operational Response to chemical incidents aim for rapid intervention to minimise injury before specialist capabilities arrive. This study examines the effectiveness of UK improvised and interim protocols conducted in sequence.

Method: A simulant with methyl salicylate (MeS) in vegetable oil and a fluorophore was applied to participants' shoulders, arms and legs.

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Article Synopsis
  • The goal of computational psychiatry is to create models that connect differences in brain function to cognitive impairments and symptoms, which are often resistant to treatment.* -
  • Research shows that to predict cognitive functioning accurately, large participant samples are needed, highlighting limitations in smaller patient studies.* -
  • Using a transfer learning approach on neuroimaging data from the UK Biobank, the study found that predictions of cognitive functioning improved significantly, even with smaller sample sizes, validating the effectiveness of training models on larger datasets.*
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Whilst the field of maternal cognition is gaining interest, with a recent increase in publications, there are still only a handful of existing studies. This presents a unique opportunity for reflection and growth, advancing scientific rigor to ensure that future interpretations of maternal cognitive functioning are based on robust, generalizable data. With this in mind, we offer ten recommendations for future cognitive research in motherhood, with a focus on intentional study design.

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