Publications by authors named "E Pilotto"
Achromatopsia (ACHM) is a rare autosomal, recessively inherited disease that is characterized by cone dysfunction, for which several gene therapies are currently on trial. The aim of this study was to find correlations between the morphological macular changes identified using optical coherence tomography (OCT) and some visual functional parameters. Visual acuity (VA), contrast sensitivity (CS), and macular sensitivity obtained by means of microperimetry were assessed.
View Article and Find Full Text PDFGeographic atrophy (GA), the atrophic late stage of age-related macular degeneration (AMD), is one of the leading causes of vision loss in developed countries. Based on genetic, histological and preclinical studies, the role of the innate immune system in the development and progression of GA is well established. Microglia, the principal resident immune cells, are recognized as key players in innate immunity and contributors to AMD development.
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- - Understanding the decay properties of the Hoyle state in carbon nuclei is crucial for calculating how much carbon is produced in red-giant stars.
- - This paper presents a new, nearly background-free method to measure the decay ratio of the Hoyle state, utilizing advanced techniques for detecting charged particles.
- - The study introduces a bidimensional map to improve measurement accuracy, providing a significant value for the radiative branching ratio and addressing discrepancies from recent research findings.
Histopathologic studies of diabetic choroid suggest that diabetic choroidopathy is a key aspect secondary to diabetes. Recently, hyperreflective choroidal foci (HCF) have been introduced as novel optical coherence tomography (OCT) parameter. The aim of this study was to identify and quantify HCF in diabetic subjects with retinopathy, with or without diabetic macular edema (DME).
View Article and Find Full Text PDFIntroduction: Microglia (MG) is suggested to play an immunopathological role of in Multiple Sclerosis (MS). Since hyper-reflective foci (HRF) might mark MG activation, analysis by Optic Coherence Tomography (OCT) in MS patients under disease modifying therapies may help to clarify MS immunopathology as well as drug's mechanism of intrathecal action.
Objective: To analyze HRF in patients treated with Natalizumab (NTZ), a high efficacy therapy for MS.