Publications by authors named "E Pignotti"
Article Synopsis
- Recent studies show a partial loss of SMARCB1/INI1 expression in skull base chordomas, suggesting potential treatment options for these tumors; this study focused on 89 patients with spinal chordomas.
- The analysis found that 41.6% of patients exhibited partial SMARCB1/INI1 loss, primarily due to a deletion on chromosome 22, with significant implications for tumor location and surgical outcomes.
- Key findings indicated that tumor location (specifically in the sacrococcygeal region) and adequate surgical margins were linked to better disease-free survival rates, highlighting important factors for patient prognosis.
Background: The minimal clinically important difference (MCID) for patient-reported outcome measures (PROMs) expresses both the extent of the improvement and the value that patients place on it. MCID use is becoming increasingly widespread to understand the clinical efficacy of a given treatment, define guidelines for clinical practice, and properly interpret trial results. However, there is still large heterogeneity in the different calculation methods.
View Article and Find Full Text PDFThe protection and promotion of agricultural niche products can be supported by the application of analytical techniques able to link food to its territory. This study aimed at exploring the possibility to discriminate between cereal samples from South Tyrol (Italy) and the neighboring regions (Trentino, East Tyrol, and North Tyrol) by their Sr/Sr ratios. Soil and grain (different species) samples were collected from around 100 fields in two sampling campaigns.
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