Publications by authors named "E Picano"
Objective: Atrial cardiomyopathy is closely associated with atrial fibrillation (AF), and some patients exhibit no dysfunction at rest but demonstrate evident changes in left atrial (LA) function and LA volume during exercise. This study aimed to identify distinguishing signs during exercise stress echocardiography (ESE) among patients in sinus rhythm (SR), with and without history of paroxysmal/persistent AF (PAF).
Methods: A prospective cohort of 1055 patients in SR was enrolled across 12 centers.
Hypercontractile phenotype (HP) of the left ventricle (LV) is an actionable therapeutic target in patients with chronic coronary syndromes (CCS) or heart failure (HF), but its clinical recognition remains difficult. To assess the clinical variables associated with the HP. In a prospective, observational, multicenter study, we recruited 5122 patients (age 65 ± 11 years, 2974 males, 58%) with CCS and/or HF with preserved ejection fraction (EF).
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- Regional wall motion abnormalities (RWMA) can be absent during stress echocardiography in patients with chronic coronary syndromes, even when coronary flow velocity reserve (CFVR) indicates significant disease.
- A study involving 749 patients showed that those with inducible RWMA had lower CFVR and that 69% underwent coronary revascularization, with 10-year survival rates significantly better in those treated invasively versus conservatively.
- The findings suggest a physiology-driven approach based on CFVR may be valuable for coronary revascularization decisions in patients with significant left anterior descending coronary artery disease.
Cardiac radiation exposure and incident cancer: challenges and opportunities.
Eur Heart J Cardiovasc Imaging
November 2024
The use of radiological procedures has enormously advanced cardiology. People with heart disease are exposed to ionizing radiation. Exposure to ionizing radiation increases lifetime cancer risk with a dose-proportional hazard according to the linear no-threshold model adopted for radioprotection purposes.
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