Non-enzymatic glycation is the chemical reaction between the amine group of an amino acid and the carbonyl group of a reducing sugar. The final products of this reaction, advanced glycation end-products (AGEs), are known to play a key role in aging and many chronic diseases. The kinetics of the AGE formation reaction depends on several factors, including pH, temperature, and the presence of prooxidant metals, such as iron and copper.
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December 2024
Physician associates (PAs) are a developing profession in the UK. The Faculty of Physician Associates (FPA) recommends the establishment of local preceptorship programmes for PAs in the first year of practice who have successfully passed the PA national exam. Limited evidence currently exists around the evaluation of such local programmes and the experience of the intern PAs involved.
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