Publications by authors named "E Pariani"
Article Synopsis
- Respiratory Syncytial Virus (RSV) primarily affects young children, especially those under 24 months old, causing severe respiratory infections, and is a global health concern according to the WHO; Nirsevimab, a long-acting monoclonal antibody, has been approved to prevent RSV in infants.
- A narrative review compiled effectiveness data on Nirsevimab, assessing the strengths and limitations of existing studies while focusing on its potential for disease prevention.
- The findings from the studies indicate that Nirsevimab is effective in real-world settings, significantly lowering hospitalizations and ICU admissions for RSV, though challenges related to supply and study variability remain; ongoing research is essential to evaluate its long-term effectiveness and
Article Synopsis
- A significant rise in enterovirus D68 (EV-D68) cases has been observed in northern Italy since July 2024, leading to an outbreak of acute respiratory infections that now represents about 90% of enterovirus infections in the region.
- Surveillance efforts, both community-based and hospital-based, have identified EV-D68 in patients with varying severity of respiratory symptoms, linking it to two specific strains, B3 and a unique A2 lineage.
- There has also been a noticeable increase in cases among adults, highlighting the need for improved surveillance and molecular analysis of EV-D68 throughout Europe.
Background: Influenza B/Yamagata viruses exhibited weak antigenic selection in recent years, reducing their prevalence over time and requiring no update of the vaccine component since 2015. To date, no B/Yamagata viruses have been isolated or sequenced since March 2020.
Methods: The antibody prevalence against the current B/Yamagata vaccine strain in Italy was investigated: For each influenza season from 2012/2013 to 2021/2022, 100 human serum samples were tested by haemagglutination inhibition (HAI) assay against the vaccine strain B/Phuket/3073/2013.
A new case of Echovirus 11 neonatal fulminant hepatitis involving male twins in a Northern Italy Tertiary University Hospital: Insight on a possible immunological clue.
IJID Reg
September 2024
The European Center for Disease Prevention and Control has reported 19 cases of severe echovirus 11 infections in neonates since 2022, nine of which were fatal. We report a new fatal neonatal case that occurred in a male twin for which we evaluated the respiratory and intestinal mucosal innate immune response.
View Article and Find Full Text PDF