[Molecular pathology of gastrointestinal neoplasms].

The molecular pathological examination of solid tumors is essential not only for supporting histological diagnosis but also for detecting hereditary variations and predictive biomarkers. Analyzing predictive markers is fundamental to personalized cancer therapy, directly affecting patient care through pathological testing. These analyses employ both traditional immunohistochemical staining methods and molecular genetic techniques.

[Predictive markers in gynaecological, prostate, and breast cancers].

The implementation of targeted therapies in oncology has brought significant improvement in the treatment of many solid tumours. At the same time, pathological and molecular pathological diagnostics became more important. Today, there are hardly any solid tumours that do not require predictive biomarker testing.

Effects of a Specific Trunk and Shoulder Strength Training Program on Throwing Velocity and Accuracy: A Study Among Hungarian First-League Female Handball Players.

The aim of the study was to record shoulder and trunk stability of elite female handball players and to investigate their effect on throwing velocity and accuracy. 151 female handball players (9 teams in total) from the Hungarian first league participated in a mid-season conditional survey. The study included tests of trunk and shoulder stability, and measurements of factors affecting shoulder stability, as well as throwing speed and throwing accuracy.

[Retrospective analysis of metaplastic breast cancer cases].

Metaplastic breast tumour is a rare, aggressive, mostly triple- negative, dedifferentiated malignancy, which poorly responds to chemotherapy compared to other invasive breast tumours. Since 2000, the WHO has considered it as a separate entity among breast tumours. Given the extremely poor prognosis of the tumour, more studies are needed to establish the most effective treatment strategy supported by data to increase overall survival.

Computation of biological conductance with Liouville quantum master equation.

Recent experiments have revealed that single proteins can display high conductivity, which stays finite for low temperatures, decays slowly with distance, and exhibits a rich spatial structure featuring highly conducting and strongly insulating domains. Here, we intruduce a new formula by combining the density matrix of the Liouville-Master Equation simulating quantum transport in nanoscale devices, and the phenomenological model of electronic conductance through molecules, that can account for the observed distance- and temperature dependence of conductance in proteins. We demonstrate its efficacy on experimentally highly conductive extracellular cytochrome nanowires, which are good candidates to illustrate our new approach by calculating and visualizing their electronic wiring, given the interest in the arrangement of their conducting and insulating parts.