Laparoscopic early pregnancy diagnosis in the laboratory rat.

Timely and accurate diagnosis of pregnancy in the laboratory rat is an invaluable endpoint in embryological and reproductive toxicology studies. The purpose of the present study was to assess the feasibility, sensitivity, accuracy and safety of laparoscopic examination of the uterus for detecting pregnancy at an early stage, and defining the number of fetuses in surviving rat models. Female Wistar rats were subjected to a two-port laparoscopic examination of their uterus from day 6 to day 10 post-coitum (pc).

Large-area versus small-area application of mitomycin C during trabeculectomy.

Purpose: To compare 2 different application methods of mitomycin C (MMC) in patients undergoing trabeculectomy.


Methods: This retrospective trial compared outcomes of 191 eyes that underwent trabeculectomy with small-area (96 eyes; 50.3%) and large-area (95 eyes; 49.

Are there filtering blebs after canaloplasty?

Purpose: Aim of the study was to assess the development of filtering blebs after canaloplasty.

Methods: Twenty eyes of 20 consecutive patients receiving canaloplasty were included. All eyes were examined clinically (slit lamp), and by anterior segment optical coherence tomography and high-frequency ultrasound biomicroscopy to detect filtering blebs.